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Catalog ID 6300 / 100 mg

DiSBAC2(3)

AKA: Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol
Formula Weight CAS#
C19H24N4O4S2 436.54 47623-98-3
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DiSBAC2(3) is a slow-response, anionic, lipophilic yellow-green-fluorescent dye that is commonly used for measurements of plasma membrane voltage potentials in live cells. The anionic oxonol dye enters depolarized cells where it binds to membranes and proteins and exhibits an increase in fluorescence intensity. Increasing depolarization in the cells results in increasing influx of the anionic dye and a corresponding increase in fluorescence intensity. Hyperpolarization in the cells indicated by a loss of fluorescence intensity within the labeled cells. DiSBAC2(3) is excited near 537 nm with an environmentally dependent fluorescence emission near 557 nm. .

Product Size 100 mg
Form Purple Solid
Absorption (estimated) Wavelength (λmax) 537 ± 3 nm (Methanol)
Fluorescence (estimated) Wavelength (λmax) 554 ± 4 nm (Methanol)
Storage conditions Store at Room Temperature (RT) Protect from moisture (D) Protect from light (L)
MDL#

* Bis-(1,3-diethylthiobarbituric acid)trimethine oxonol
* 4,6(1H,5H)-Pyrimidinedione, 5-(3-(1,3-diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl) -2-propenylidene)-1,3-diethyldihydro-2-thioxo-

Fluorescent Probes and Related Products:   Oxonol
Cellular Sensors, Ion and pH Indicators (Fluorescent/Non-Fluorescent):   Voltage and Membrane Potential Sensors

Safety Data Sheet
SDS-PDF
Certificates of Analysis
Lot 51806 29-Apr-2020

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