Product 6204

In Stock

Catalog ID 6204 / 5 mg

5-TAMRA, maleimide single isomer

AKA: Tetramethylrhodamine-5-maleimide

Formula	Weight	CAS#
C₂₈H₂₃N₃O₅	481.51	174568-67-3

1-4 - ¤ 247/Unit 5-24 - ¤ 233/Unit

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5-TAMRA maleimide is an orange-fluorescent, single isomer, thiol-reactive dye for synthesis of orange fluorescent biomolecules. The maleimide group is selective for reaction with thiol groups on peptides, proteins, and other thiol-containing biomolecules when reacted at pH below 7.5. 5-TAMRA maleimide, sometimes also referred to as TMRM, has been used for investigations of conformational changes in voltage sensitive domains of ion channels by site directed fluorescent labeling. Conjugates of 5-TAMRA maleimide are excited near 541 nm with fluorescence emission near 567 nm and are relatively photostable and insensitive to changes in pH. 5-TAMRA maleimide is a purified single isomer label that is suitable for preparing conjugates that are purified by capillary electrophoresis or ion-exchange chromatography.

Product Size	5 mg
Form	Red Solid
Absorption (estimated)	Wavelength (λmax) 541 ± 3 nm (Methanol)
Fluorescence (estimated)	Wavelength (λmax) 567 ± 4 nm (Methanol)
Storage conditions	Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#	MFCD01311091

* Tetramethylrhodamine-5-maleimide
* Xanthylium, 9-(2-carboxy-5-(2,5-dihydro-2,5-dioxo-1h-pyrrol-1-yl) phenyl)-3,6-bis(dimethylamino)-, inner salt
* Tetramethylrhodamine - 5 - maleimide

Label or Dye:	Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA
Fluorescent Probes and Related Products:	Rhodamine/Rosamine
Reactive Probes and Related Products:	Thiol-Reactive (Haloacetamide/Halobenzyl and Maleimide)