Product 8110

CellHunt Green 8-P2M is a green-fluorescent, thiol-reactive dye that is relatively selective for reaction with thiol groups when reacted at pH below 7.5. CellHunt Green 8-P2M may have applications as a long-term fluorescent cell tracer dye. CellHunt Green 8-P2M exhibits a fluorescence that is strongly quenched, presumably through a photoinduced electron transfer mechanism, until the maleimide group reacts with a thiol group. Reaction with a thiol group restores the green-fluorescence with a high quantum yield. CellHunt Green 8-P2M is also useful for preparing green-fluorescent conjugates of peptides, proteins, and other biomolecules that contain thiol groups. CellHunt Green 8-P2M is non-ionic, non-toxic, and is relatively insensitive to changes in pH and environment. .