Product 9199
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Catalog ID 9199 / 5 mg
DBF *Cytochrome P450 Substrate*
AKA: Dibenzylfluorescein
Formula | Weight | CAS# |
---|---|---|
C34H24O5 | 512.55 | 97744-44-0 |
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DBF is dealkylated by cytochromes P450 (especially CYP2C8, CYP2C9, CYP2C19, and CYP3A) to form a fluorescein ester. Dibenzylfluorescein was reported to be suitable for in vitro assessment of the initial screening of CYP3A4- mediated drug interactions. The fluorescent fluorescein product can be quantitated after the addition of base, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection.
Product Size | 5 mg |
---|---|
Form | Orange Solid |
Absorption (estimated) | Wavelength (λmax) 458 ± 3 nm (Methanol) |
Storage conditions | Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L) |
MDL# | MFCD13184323 |
* Dibenzylfluorescein
* Benzyl 2-(6-(benzyloxy)-3-oxo-3H-xanthen-9-yl)benzoate
* NSC 645658
* Benzyl 2-(6-(benzyloxy)-3-oxo-3H-xanthen-9-yl)benzoate
* NSC 645658
Enzyme Detection, Substrates and Activity Assays : | Cytochrome P450 Substrates |
---|---|
Fluorescent Probes and Related Products: | Fluorescein, Naphthofluorescein and seminaphthofluorescein |
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