Product 6284

Lead Time 3 Weeks

Catalog ID 6284 / 5 mg

BZAR

AKA: Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt

Formula	Weight	CAS#
C₁₄H₂₁ClN₄O₄	344.80	N/A

1-4 - ¤ 146/Unit 5-24 - ¤ 133/Unit

For 25+ Units, Contact us.

BZAR is a fluorogenic enzyme substrate for serine proteases. BZAR is non-fluorescent and colorless until enzymatic activity results in cleavage of one of the amide bonds and converts the non-fluorescent bis-amide substrate into a highly fluorescent monoamide product. Enzymatic activity is detected by fluorescence with an excitation near 492 nm and emission near 523 nm. BZAR is recognized for providing much greater sensitivity to enzymatic activity than similar coumarin-based fluorogenic-enzymatic assays. BZAR is also a known inhibitor of guanidinobenzoatase activity in tumor cells. .

Product Size	5 mg
Form	Orange solid
Absorption (estimated)	Wavelength (λmax) 232 ± 3 nm (Methanol)
Storage conditions	Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt
* Rhodamine 110, bis-(Z-L-Arg amide), dihydrochloride salt
* R110, bis-(Z-L-Arg amide), 2HCl salt

Enzyme Detection, Substrates and Activity Assays :	Protease and Peptidase Substrates
Label or Dye:	Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA
Fluorescent Probes and Related Products:	Rhodamine/Rosamine