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Catalog ID 6853 / 5 mg

Z-DEVD-R 110 for detection of caspases 3 and 7

AKA: Rhodamine 110, bis-(N-CBZ-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid amide
Formula Weight CAS#
C27H78N10O27 1,515.45 N/A
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Rhodamine 110 (R110)-derived substrates are locked in the lactone configuration are non-fluorescent. Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments. R110-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. This R110 substrate is specific for caspases 3 and 7.

Product Size 5 mg
Form Off-white solid
Storage conditions Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Rhodamine 110, bis-(N-CBZ-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid amide
* R 110, CBZ-Asp-Glu-Val-Asp
* (Z-DEVD)2-R110

Enzyme Detection, Substrates and Activity Assays :   Caspase
Enzyme Detection, Substrates and Activity Assays :   Protease and Peptidase Substrates
Label or Dye:   Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA
Fluorescent Probes and Related Products:   Rhodamine/Rosamine

Safety Data Sheet
SDS-PDF
Certificates of Analysis
Lot 50245 08-Dec-2014

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