Product 6853

In Stock

Catalog ID 6853 / 5 mg

Z-DEVD-R 110 for detection of caspases 3 and 7

AKA: Rhodamine 110, bis-(N-CBZ-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid amide

Formula	Weight	CAS#
C₂₇H₇₈N₁₀O₂₇	1,515.45	N/A

1-4 - ¤ 284/Unit 5-24 - ¤ 270/Unit

For 25+ Units, Contact us.

Rhodamine 110 (R110)-derived substrates are locked in the lactone configuration are non-fluorescent. Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments. R110-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. This R110 substrate is specific for caspases 3 and 7.

Product Size	5 mg
Form	Off-white solid
Storage conditions	Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Rhodamine 110, bis-(N-CBZ-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid amide
* R 110, CBZ-Asp-Glu-Val-Asp
* (Z-DEVD)2-R110

Enzyme Detection, Substrates and Activity Assays :	Caspase
Enzyme Detection, Substrates and Activity Assays :	Protease and Peptidase Substrates
Label or Dye:	Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA
Fluorescent Probes and Related Products:	Rhodamine/Rosamine