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Catalog ID 6162 / 1 mg

    Other Unit Sizes:    6163 / 1 mg    6164 / 20 x 50 ug   

Mag-fura-2, AM *Cell Permeant*

AKA: Furaptra, AM ester
Formula Weight CAS#
C30H30N2O19 722.57 130100-20-8
For 25+ Units, Contact us.

Mag-fura-2, AM is a cell membrane-permeant, short-wavelength fluorescent ion indicator for intracellular magnesium ion measurements. Mag-fura-2’s spectral response to ion-binding permits a ratiometric calculation of ion concentration that cancels artifacts of photobleaching, dye concentration gradients, cell thickness and dye leakage. Live cells are passively loaded with Mag-Fura-2, AM by incubation with the cell-membrane permeant AM esters. Once internalized, cytosolic esterases cleave the AM esters to liberate the active tetra-carboxylate ligand. The excitation wavelength of Mag-fura-2 varies with Mg2+ concentration and shifts to shorter wavelengths with increasing Mg2+ concentration. The ratio of fluorescence intensity at 510 nm when excited at 340/380 nm is used for ratiometric calculation of ion concentration. Mag-fura-2 has also been used as a low affinity fluorescent indicator for intracellular Ca2+ measurements where high concentration Ca2+ transients would saturate higher affinity indicators. .

Product Size 1 mg
Form Lite Yellow Solid
Absorption (estimated) Wavelength (λmax) 366 ± 3 nm (Ethyl acetate)
Fluorescence (estimated) Wavelength (λmax) 472 ± 4 nm (Ethyl acetate)
Storage conditions Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Furaptra, AM ester
* 5-Oxazolecarboxylic acid, 2-[5-[2-[(acetyloxy)methoxy]-2-oxoethoxy]-6-[bis[2-[ (acetyloxy)methoxy]-2-oxoethyl]amino]-2-benzofuranyl] -(acetyloxy)methyl ester

Cellular Sensors, Ion and pH Indicators (Fluorescent/Non-Fluorescent):   Fluorescent Calcium Indicators
Fluorescent Probes and Related Products:   Fluorescent Indicators (Ca, Cl, K, Mg, Na, Zn)
Cellular Sensors, Ion and pH Indicators (Fluorescent/Non-Fluorescent):   Fluorescent Magnesium Indicators
Label or Dye:   Fura-2 / Fura-4 / Fura-5 / Fura-FF / Mag-fura

Safety Data Sheet
SDS-PDF
Certificates of Analysis
Lot 50595 14-Sep-2015
Lot 50597 14-Sep-2015

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