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Catalog ID 6278 / 5 mg

Rh110-2(Asp) *D2R* *D)2-Rh 110 (trifluoroacetate salt)*

AKA: Rhodamine 110, bis-(L-aspartic acid amide), trifluoroacetic acid salt
Formula Weight CAS#
C32H26F6N4O13 788.57 220846-63-9
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Rh110-2(Asp) is a cell-permeant fluorogenic enzyme substrate for the caspase proteases that are associated with apoptosis. Rh110-2(Asp) is a common substrate for the caspases, a family of enzymes that exhibit proteolytic activity targeting aspartic acid (Asp) in the P1 position of substrates. Rh110-2(Asp) is non-fluorescent until enzymatic cleavage of the Asp groups liberates the green-fluorescent Rh110 dye in a two-step hydrolysis pathway. Enzymatic activity is detected by fluorescence with the excitation near 496 nm and fluorescent emission near 520 nm. .

Product Size 5 mg
Form Off White Solid
Absorption (estimated) Wavelength (λmax) 234 ± 3 nm (Water)
Storage conditions Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Rhodamine 110, bis-(L-aspartic acid amide), trifluoroacetic acid salt
* (L-Asp)2 rhodamine 110 • TFA salt
* Butanoic acid, 4,4'-[(3-oxospiro[isobenzofuran-1(3H0,9'-[9H]xanthene]-3'6'-diyl)diimino]bis[3-amino-4-oxo-, (3S,3'S)-, bis(trifluoroacetate)]

Enzyme Detection, Substrates and Activity Assays :   Caspase
Enzyme Detection, Substrates and Activity Assays :   Protease and Peptidase Substrates
Label or Dye:   Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA
Fluorescent Probes and Related Products:   Rhodamine/Rosamine

Safety Data Sheet
SDS-PDF
Certificates of Analysis
Lot 50935 16-Sep-2014

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