Product 6064
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Catalog ID 6064 / 25 mg
bBBR
AKA: Dibromobimane
Formula | Weight | CAS# |
---|---|---|
C10H10Br2N2O2 | 350.00 | 68654-25-1 |
For 25+ Units, Contact us.
Dibromobimane is a low molecular weight, non-ionic, fluorescent probe for labeling thiols and crosslinking proteins. This cell-permeant probe is essentially non-fluorescent until both bromomethyl groups have reacted with thiols. The bromomethyl groups are relatively selective for reaction with thiols at physiological pH but may also react with carboxylates at pH above 7. Dibromobimane has been used to form an intramolecular-crosslink in myosin, hemoglobin, ATPase and other thiol-containing proteins. The conjugates of Dibromobimane are optimally excited near 394 nm and have a variable emission near 490 nm.
Product Size | 25 mg |
---|---|
Form | Yellow Solid |
Absorption (estimated) | Wavelength (λmax) 360 ± 3 nm (Methanol) |
Fluorescence (estimated) | Wavelength (λmax) 477 ± 4 nm (*Buffer pH 7) |
Storage conditions | Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L) |
MDL# |
* Dibromobimane
* 1H,7H-Pyrazolo(1,2-?)pyrazole-1,7-dione, 3,5-bis(bromomethyl)-2,6-dimethyl-
* 1H,7H-Pyrazolo(1,2-?)pyrazole-1,7-dione, 3,5-bis(bromomethyl)-2,6-dimethyl-
Fluorescent Probes and Related Products: | Bimane |
---|---|
Reactive Probes and Related Products: | Thiol-Reactive (Haloacetamide/Halobenzyl and Maleimide) |
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