Product 6270
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Catalog ID 6270 / 100 mg
MQAE
AKA: 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
Formula | Weight | CAS# |
---|---|---|
C14H16BrNO3 | 326.19 | 162558-52-3 |
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MQAE is a halide-sensitive blue-fluorescent probe that is used to monitor chloride transport and efflux mechanisms in living cells. MQAE is more sensitive to chloride ion than the related commonly used chloride indicator, SPQ (product 7115). MQAE also has a brighter fluorescence quantum yield than SPQ and therefore is more commonly used for fluorescence measurements of chloride ion transport. However, the ester group of MQAE may be slowly hydrolysed by cytosolic esterases in live cells, resulting in changes in the dye’s fluorescence response to halide ions. MQAE is excited near 353 nm with an environmentally dependent fluorescence emission near 462 nm and exhibits a fluorescence quenching response to halide ions (collisional quenching). .
Product Size | 100 mg |
---|---|
Form | Lite Orange Solid |
Absorption (estimated) | Wavelength (λmax) 353 ± 3 nm (Methanol) |
Fluorescence (estimated) | Wavelength (λmax) 462 ± 4 nm (Methanol) |
Storage conditions | Store at Room Temperature (RT) Protect from moisture (D) Protect from light (L) |
MDL# |
* 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
* 6-(Methoxyquinolinio)acetic acid ethyl ester bromide
* 6-(Methoxyquinolinio)acetic acid ethyl ester bromide
Cellular Sensors, Ion and pH Indicators (Fluorescent/Non-Fluorescent): | Fluorescent Chloride Indicators |
---|---|
Fluorescent Probes and Related Products: | Fluorescent Indicators (Ca, Cl, K, Mg, Na, Zn) |
Fluorescent Probes and Related Products: | Quinoline |
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