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Product 6284

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Lead Time 3 Weeks

Catalog ID 6284 / 5 mg

BZAR

AKA: Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt
Formula Weight CAS#
C14H21ClN4O4 344.80 N/A
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BZAR is a fluorogenic enzyme substrate for serine proteases. BZAR is non-fluorescent and colorless until enzymatic activity results in cleavage of one of the amide bonds and converts the non-fluorescent bis-amide substrate into a highly fluorescent monoamide product. Enzymatic activity is detected by fluorescence with an excitation near 492 nm and emission near 523 nm. BZAR is recognized for providing much greater sensitivity to enzymatic activity than similar coumarin-based fluorogenic-enzymatic assays. BZAR is also a known inhibitor of guanidinobenzoatase activity in tumor cells. .

Product Size 5 mg
Form Orange solid
Absorption (estimated) Wavelength (λmax) 232 ± 3 nm (Methanol)
Storage conditions Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt
* Rhodamine 110, bis-(Z-L-Arg amide), dihydrochloride salt
* R110, bis-(Z-L-Arg amide), 2HCl salt

Enzyme Detection, Substrates and Activity Assays :   Protease and Peptidase Substrates
Label or Dye:   Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA
Fluorescent Probes and Related Products:   Rhodamine/Rosamine

Safety Data Sheet
SDS-PDF

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