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Catalog ID 6270 / 100 mg

MQAE

AKA: 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
Formula Weight CAS#
C14H16BrNO3 326.19 162558-52-3
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MQAE is a halide-sensitive blue-fluorescent probe that is used to monitor chloride transport and efflux mechanisms in living cells. MQAE is more sensitive to chloride ion than the related commonly used chloride indicator, SPQ (product 7115). MQAE also has a brighter fluorescence quantum yield than SPQ and therefore is more commonly used for fluorescence measurements of chloride ion transport. However, the ester group of MQAE may be slowly hydrolysed by cytosolic esterases in live cells, resulting in changes in the dye’s fluorescence response to halide ions. MQAE is excited near 353 nm with an environmentally dependent fluorescence emission near 462 nm and exhibits a fluorescence quenching response to halide ions (collisional quenching). .

Product Size 100 mg
Form Lite Orange Solid
Absorption (estimated) Wavelength (λmax) 353 ± 3 nm (Methanol)
Fluorescence (estimated) Wavelength (λmax) 462 ± 4 nm (Methanol)
Storage conditions Store at Room Temperature (RT) Protect from moisture (D) Protect from light (L)
MDL#

* 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
* 6-(Methoxyquinolinio)acetic acid ethyl ester bromide

Cellular Sensors, Ion and pH Indicators (Fluorescent/Non-Fluorescent):   Fluorescent Chloride Indicators
Fluorescent Probes and Related Products:   Fluorescent Indicators (Ca, Cl, K, Mg, Na, Zn)
Fluorescent Probes and Related Products:   Quinoline

Safety Data Sheet
SDS-PDF
Certificates of Analysis
Lot 50610 29-Sep-2015

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