Product 6115
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Catalog ID 6115 / 25 mg
qBBr
AKA: Monobromotrimethylammoniobimane bromide
Formula | Weight | CAS# |
---|---|---|
C13H19Br2N3O2 | 409.12 | 71418-45-6 |
For 25+ Units, Contact us.
qBBr is a low molecular weight, fluorescent probe for labeling thiols. This probe is essentially non-fluorescent until it reacts with a thiol group. The bromomethyl group is relatively selective for reaction with thiols at physiological pH but may also react with carboxylates at pH above 7. Unlike related bimane probes that are readily cell-permeant, the trimethylammonium group inhibits the membrane-permeability of qBBr. This probe is used as a derivatization agent for thiol containing molecules and contains a positive charge that facilitates the separation of conjugates by electrophoresis or ion-exchange chromatography. The conjugates of qBBr are optimally excited near 394 nm and have a variable emission near 490 nm.
Product Size | 25 mg |
---|---|
Form | Yellow Solid |
Absorption (estimated) | Wavelength (λmax) 377 ± 3 nm (Buffer pH 8) |
Storage conditions | Refrigerate: Store at 4-8°C (Ref) Protect from moisture (D) Protect from light (L) |
MDL# | MFCD00036953 |
* Monobromotrimethylammoniobimane bromide
* 1H,7H-pyrazolo (1,2-a)pyrozole-3-methanaminium, 5-bromomethyl)-N,N,N,2,6-pentamethyl-1,7-dioxo, bromide
* 1H,7H-pyrazolo (1,2-a)pyrozole-3-methanaminium, 5-bromomethyl)-N,N,N,2,6-pentamethyl-1,7-dioxo, bromide
Fluorescent Probes and Related Products: | Bimane |
---|---|
Reactive Probes and Related Products: | Thiol-Reactive (Haloacetamide/Halobenzyl and Maleimide) |
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