Product 9169

In Stock

Catalog ID 9169 / 100 ug

EverFluor FL Thapsigargin

Formula	Weight	CAS#
C₄₄H₅₇BF₂N₂O₁₂	854.74	216571-99-2

1-4 - ¤ 377/Unit 5-24 - ¤ 355/Unit

For 25+ Units, Contact us.

EverFluor FL Thapsigargin is a cell-permeant, green-fluorescent probe for investigations of thapsigargin binding sites in live cells. Thapsigargin is a naturally occurring sesquiterpene lactone and a potent inhibitor of plasma membrane Ca²⁺ ATPases that blocks the cell’s ability to actively pump calcium into the sarcoplasmic reticulum and endoplasmic reticulum, resulting in an increasing influx of calcium into the cytosol. Thapsigargin also inhibits the fusion of lysosomes to autophagosomes, leading to stress on the endoplasmic reticulum. Our brightly fluorescent EverFluor FL dye is optimally excited at 503 nm, non-ionic, and is relatively insensitive to environmental and pH changes. .

Product Size	100 ug
Form	Yellow Solid
Absorption (estimated)	Wavelength (λmax) 503 ± 3 nm (Methanol)
Fluorescence (estimated)	Wavelength (λmax) 510 ± 4 nm (Methanol)
Storage conditions	Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* Known as BODIPY® FL Thapsigargin *TM of Molecular Probes*

Conjugated Biomolecules / Bioconjugates:	Biochemical, Drug & Antibiotic Conjugates
Fluorescent Probes and Related Products:	EverFluor (Known as BODIPY, TM of Molecular Probes)
Label or Dye:	EverFluor FL (Known as BODIPY FL, TM of Molecular Probes)
Excitation and Emision Ranges:	Excitation: 500-505 nm and Emission: 508-515 nm
Natural Products and Their Fluorescent/Non-Fluorescent Conjugates:	Fluorescent/Non-Fluorescent Conjugates