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Catalog ID 6030 / 5 mg

AMCA, SE

AKA: 7-Amino-4-methyl-3-coumarin acetic acid, succinimidyl ester
Formula Weight CAS#
C16H14N2O6 330.30 113721-87-2
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AMCA, SE is a commonly used blue-fluorescent, amine-reactive dye for the synthesis of blue-fluorescent biomolecules. The SE-activated ester is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers and other amine-containing biomolecules. Conjugates of AMCA dye have a pH-dependent and environmentally sensitive fluorescence and are excited near 355 nm with emission near 440 nm. .

Product Size 5 mg
Form Off White Solid
Absorption (estimated) Wavelength (λmax) 354 ± 3 nm (Methanol)
Fluorescence (estimated) Wavelength (λmax) 440 ± 4 nm (Methanol)
Storage conditions Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* 7-Amino-4-methyl-3-coumarin acetic acid, succinimidyl ester
* Ssuccinimydyl-7-amino-4-methylcoumarin-3-acetic acid,, NHS-AMCA
* 2,5-Pyrrolidinedione, 1-[[(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-yl)acetyl]oxy]-

Reactive Probes and Related Products:   Activated, Amine-Reactive [Isothiocyanate, Succinimydyl Ester (SE), Sulfonyl Halide, TFP Ester, NBD-Cl, NBD-F, etc.]
Amine-Reactive Fluorophores, Biotins and Other Labels:   Active Ester - Succinimidyl Ester (SE or NHS-ester)
Fluorescent Probes and Related Products:   Coumarin (Umbelliferone)
Label or Dye:   Coumarin (Umbelliferone) and Methylcoumarin
Excitation and Emision Ranges:   Excitation: 345-360 nm and Emission: 430-450 nm

Safety Data Sheet
SDS-PDF
Certificates of Analysis
Lot 51982 22-Mar-2021

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