Product 6278
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Catalog ID 6278 / 5 mg
Rh110-2(Asp) *D2R* *D)2-Rh 110 (trifluoroacetate salt)*
AKA: Rhodamine 110, bis-(L-aspartic acid amide), trifluoroacetic acid salt
Formula | Weight | CAS# |
---|---|---|
C32H26F6N4O13 | 788.57 | 220846-63-9 |
For 25+ Units, Contact us.
Rh110-2(Asp) is a cell-permeant fluorogenic enzyme substrate for the caspase proteases that are associated with apoptosis. Rh110-2(Asp) is a common substrate for the caspases, a family of enzymes that exhibit proteolytic activity targeting aspartic acid (Asp) in the P1 position of substrates. Rh110-2(Asp) is non-fluorescent until enzymatic cleavage of the Asp groups liberates the green-fluorescent Rh110 dye in a two-step hydrolysis pathway. Enzymatic activity is detected by fluorescence with the excitation near 496 nm and fluorescent emission near 520 nm. .
Product Size | 5 mg |
---|---|
Form | Off White Solid |
Absorption (estimated) | Wavelength (λmax) 234 ± 3 nm (Water) |
Storage conditions | Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L) |
MDL# |
* Rhodamine 110, bis-(L-aspartic acid amide), trifluoroacetic acid salt
* (L-Asp)2 rhodamine 110 • TFA salt
* Butanoic acid, 4,4'-[(3-oxospiro[isobenzofuran-1(3H0,9'-[9H]xanthene]-3'6'-diyl)diimino]bis[3-amino-4-oxo-, (3S,3'S)-, bis(trifluoroacetate)]
* (L-Asp)2 rhodamine 110 • TFA salt
* Butanoic acid, 4,4'-[(3-oxospiro[isobenzofuran-1(3H0,9'-[9H]xanthene]-3'6'-diyl)diimino]bis[3-amino-4-oxo-, (3S,3'S)-, bis(trifluoroacetate)]
Enzyme Detection, Substrates and Activity Assays : | Caspase |
---|---|
Enzyme Detection, Substrates and Activity Assays : | Protease and Peptidase Substrates |
Label or Dye: | Rhodamine / Rosamine / TMR (Tetramethylrhodamine) / TAMRA |
Fluorescent Probes and Related Products: | Rhodamine/Rosamine |
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