Product 6825

In Stock

Catalog ID 6825 / 500 mg

Other Unit Size: 8007 / 1 g

4-MU-sulfate K

AKA: 4-Methylumbelliferyl sulfate, potassium salt

Formula	Weight	CAS#
C₁₀H₇O₆SK	294.33	15220-11-8

1-4 - $ 133/Unit 5-24 - $ 126/Unit

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4-Methylumbelliferyl sulfate, potassium salt is a coumarin derivative and highly sensitive fluorescent substrate for monitoring aryl sulfatase activity. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.

Product Size	500 mg
Form	White Solid
Absorption (estimated)	Wavelength (λmax) 311 ± 3 nm (Buffer pH 10)
Storage conditions	Freeze: Store at -5 to -30°C (F) Protect from moisture (D) Protect from light (L)
MDL#

* 4-Methylumbelliferyl sulfate, potassium salt

Fluorescent Probes and Related Products:	Coumarin (Umbelliferone)
Label or Dye:	Coumarin (Umbelliferone) and Methylcoumarin
Enzyme Detection, Substrates and Activity Assays :	Sulfatase Substrates