Catalog ID: 6117 UNIT SIZE: 100 mg

APPC [4-Aminophenylphosphorylcholine] 100 mg

MOL. FORMULA

C11H19N2O4P

MOL. WEIGHT

274.26

CAS NUMBER

102185-28-4

MDL NUMBER

MFCD00063476

Description

4-Aminophenyl phosphorylcholine is a reactive hapten that may be used for the preparation of solid phase supports for affinity chromatography purification of phosphorylcholine-binding proteins. The p-aminophenyl group may be used to covalently bond this phosphorylcholine ligand to solid phase supports like agarose beads, modified glass beads, polystyrene beads, dextran, cellulose, polyacrylamide, and latex. The immobilized ligand may then be used to bind and capture phosphorylcholine-binding proteins and to separate those proteins from other matrix impurities. The bound protein is then recovered in its native and highly purified form by changing conditions to favor the elution from the solid phase support. The p-aminophenyl group may also be used as a building block for the synthesis of reactive ligands like isothiocyanates, maleimides, and iodoacetamides. Please also see bottom of the page for more related products.

Images

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Documents

Safety Data Sheet

SDS: SDS 6117, 7761.pdf

Certificate of Analysis

Lot Number: production lot 14953
Lot Number: 50726
Lot Number: 51457
Lot Number: 51654
Lot Number: 51669

Product Manuals

No Documents Available

Storage

Storage Condition
Store -5 to -30^oC (F)	Protect from Moisture (D)	Protect from Light (L)

Product Information

Product Specification Information

Catalog number: 6117

Name: APPC [4-Aminophenyl phosphorylcholine]

HPLC Purity: ≥ 95% at 254 nm

Absorption:

Wavelength Maximum λ_max: 293 ± 3 nm in Methanol

Extinction Coefficient: 1,700 ± 150 cm^-1 M^-1

NMR: D₂O

TLC: ≥ 95%

Appearance/Form: Off-white Solid

Solubility: DMSO, DMF, dilute Methanol and Water

Synonyms

• 2-[(4-AMINOPHENOXY)-OXIDO-PHOSPHORYL]OXYETHYL-TRIMETHYL-AZANIUM

• 4-aminophenyl (2-(trimethylammonio)ethyl) phosphate

• PAPPC

• Ethanaminium

• 2-[[(4-aminophenoxy) hydroxyphosphinyl] oxy]-N,N,N-trimethyl-, inner salt

• 4-Aminophenyl phosphorylcholine

• Phosphocholine 4-aminophenyl ester

• O-(4-aminophenylphosphoryl)choline

Citations And References

• Arch Biochem Biophys. 341-9 (1993)

• Bruderer, U., et al.: Mol. Immunol., 26, 63 (1989)

Regulatory Compliance

For Research Use Only. Not for any animal or human therapeutic or diagnostic use No Animal source
Regulatory Compliance
6117	4-Aminophenylphosphorylcholine [APPC]
OSHA Hazard			No Known OSHA Hazards
HMIS Classification			Health: 0	Flammability: 0		Physical Hazard: 0
NFPA Rating			Health: 0	Fire: 0			Reactivity: 0
TSCA Status			Not On TSCA Inventory
Transportation Information
DOT (US)		IMDG			IATA
Not Dangerous Good		Not Dangerous Good			Not Dangerous Good