NP-EGTA, AM *Cell Permeant*

Catalog ID: 6637 UNIT SIZE: 1 mg

NP-EGTA, AM *Cell Permeant*

o-Nitrophenyl EGTA, AM

C32H43N3O20
789.70
N/A
N/A
1-4 ($229.00/Unit) 5-24 ($205.00/Unit) 25-49 ($181.00/Unit)

Description

Non Fluorescent Photolabile chelator probe cell-permeant NP-caged EGTA, AM is converted to NP-EGTA by intracellular esterases, which exhibits a high selectivity for Ca2+ upon UV illumination, its Kd increases from 80 nM to >1 mM.

Images

No Images Available

Documents

Safety Data Sheet
SDS: SDS-6637.pdf

Certificate of Analysis
Lot Number: 50628

Product Manuals
No Documents Available


 

 

Storage Condition

Store -5 to -30oC (F)

Protect from Moisture (D)

Protect from Light (L)

 

 

 

Product Specification Information

Catalog number: 6637     

Name:  NP-EGTA, AM *Cell Permeant*

o-Nitrophenyl EGTA, AM

HPLC Purity: ≥ 90% at 254 nm

Absorption:

Wavelength Maximum λmax: 250 ± 3 nm in Acetonitrile

Extinction Coefficient: 4,200 ± 400 cm-1 M-1

NMR:  CDCl3

TLC:  ≥ 90%

Appearance/Form: Yellow Oil

Solubility: DMSO, DMF, Acetonitrile, Ethyl Acetate and Chloroform

 

 

 

  • • Bis(acetoxymethyl) 3,12-bis(2-(acetoxymethoxy)-2-oxoethyl)-4-(2-nitrophenyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioate

  • Caged o-Nitrophenyl EGTA, AM

Selective induction of LTP and LTD by postsynaptic [Ca2+]i elevation." Yang SN, Tang YG, Zucker RS. J Neurophysiol 81, 781-787 (1999)

Nitrophenyl-EGTA, a photolabile chelator that selectively binds Ca2+ with high affinity and releases it rapidly upon photolysis." Ellis-Davies GC, Kaplan JH. Proc Natl Acad Sci U S A 91, 187-191 (1994)

 

For Research Use Only. Not for any animal or human therapeutic

or diagnostic use

No Animal source

Regulatory Compliance

6637

o-Nitrophenyl EGTA, AM  [NP-EGTA, AM]

OSHA Hazard

No Known OSHA Hazards

HMIS Classification

Health: 0

Flammability: 0

Physical Hazard: 0

NFPA Rating

Health: 0

Fire:  0

Reactivity: 0

TSCA Status

Not On TSCA Inventory

Transportation Information

DOT (US)

IMDG

IATA

Not dangerous goods

Not dangerous goods

Not dangerous goods