Z-DEVD-R 110 for detection of caspases 3 and 7

Catalog ID: 6853 UNIT SIZE: 5 mg

Z-DEVD-R 110 for detection of caspases 3 and 7

Rhodamine 110, bis-(N-CBZ-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid amide [Caspase Substrate]

C27H78N10O27
1515.45
N/A
N/A
1-4 ($259.00/Unit) 5-24 ($246.00/Unit) 25-49 ($233.00/Unit)

Description

Rhodamine 110 (R110)-derived substrates are locked in the lactone configuration are non-fluorescent. Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments. R110-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. This R110 substrate is specific for caspases 3 and 7.

Documents

Safety Data Sheet
SDS: SDS 6853.pdf
Certificate of Analysis
Lot Number: 14311-1
Lot Number: 50245-10/2/19
Product Manuals
No Documents Available

Images

No Images Available

Product Information

Product Size 5 mg
Form Solid
Category Enzyme Substrates:
Caspase,
Protease and Peptidase Substrates
Category Fluorescent Probes and Related Products:
Rhodamine/Rosamine
Storage conditions Freeze: Store at -5 to -30°C (F)
Protect from moisture (D)
Protect from light (L)
Shipping conditions Room temperature
  • • R 110, CBZ-Asp-Glu-Val-Asp

• Staurosporine-induced apoptosis in human cornea epithelial cells in vitro." Hartel S, Zorn-Kruppa M, Tykhonova S, Alajuuma P, Engelke M, Diehl HA. Cytometry A 55, 15-23 (2003).
 
• A role for hyrogen peroxide in the pro-apoptotic effects of photodynamic therapy, Price M, Terlecky SR, Kessel D, Journal, Photochem Photobiol (2009) 85:1491-1496


 

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For Research Use Only. Not for any animal or human therapeutic

or diagnostic use

No Animal source

Regulatory Compliance

6853

Z-DEVD-R 110  [Rhodamine 110, bis-(N-CBZ-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid amide]

OSHA Hazard

No Know OSHA Hazards

HMIS Classification

Health: 0

Flammability: 0

Physical Hazard: 0

NFPA Rating

Health: 0

Fire:  0

Reactivity: 0

TSCA Status

Not On TSCA Inventory

Transportation Information

DOT (US)

IMDG

IATA

Not Dangerous Good

Not Dangerous Good

Not Dangerous Good

 

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