Oxonol V

Catalog ID: 6632 UNIT SIZE: 100 mg

Oxonol V

Bis-(3-phenyl-5-oxoisoxazol-4-yl)pentamethine oxonol

C23H16N2O4
384.38
61389-30-8
MFCD00075232
1-4 ($212.00/Unit) 5-24 ($199.00/Unit)

Description

Oxonol V is a sensitive slow-response probe for measuring cellular membrane potential. In general, slow-response probes exhibit potential-dependent changes in their transmembrane distribution that are accompanied by a fluorescence change. Please also see bottom of the page for more related products.

Images

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Documents

Safety Data Sheet
No Documents Available
Certificate of Analysis
No Documents Available
Product Manuals
No Documents Available


 

Storage Condition

Protect from Light (PL)

Protect from Moisture (PM)

Store at Room Temperature (RT)

 

 

Analytical data & Specification

6632

Oxonol V  [Bis-(3-phenyl-5-oxoisoxazol-4-yl)pentamethine oxonol]

 

Standard

Observed

HPLC Purity

≥90%

95%

Absorption: λEx  

Methanol

610 ± 3 nm

 

Fluorescence: λEm 

Methanol

640 ± 4 nm

 

Extinction coefficient

133,000 ± 9,000 cm-1 M-1

NMR

d6-DMSO

TLC

≥90%

95%

Appearance/Form

Brown solid

Solubility

DMSO, DMF and Methanol

 

  • • 5(4H)-Isoxazolone, 4-(5-(5-hydroxy-3-phenyl-4-isoxazolyl)-2,4-pentadienylidene)-3-phenyl

• Ratiometric fluorescence measurements of membrane potential generated by yeast plasma membrane H(+)-ATPase reconstituted into vesicles." Holoubek A, Vecer J, Opekarova M, Sigler K. Biochim Biophys Acta 1609, 71-9 (2003)

• The Escherichia coli multidrug transporter MdfA catalyzes both electrogenic and electroneutral transport reactions." Lewinson O, Adler J, Poelarends GJ, Mazurkiewicz P, Driessen AJ, Bibi E. Proc Natl Acad Sci U S A 100, 1667-72 (2003)

• Proton-motive force stimulates the proteolytic activity of FtsH, a membrane-bound ATP-dependent protease in Escherichia coli." Akiyama Y. Proc Natl Acad Sci U S A 99, 8066-71 (2002)

• Anomalous response of oxonol-V to membrane potential in mitochondrial proton pumps." Ahmed I, Krishnamoorthy G. Biochim Biophys Acta 1188, 131-138 (1994)

 

For Research Use Only. Not for any animal or human therapeutic

or diagnostic use

No Animal source

Regulatory Compliance

6632

Oxonol V  [Bis-(3-phenyl-5-oxoisoxazol-4-yl)pentamethine oxonol]

OSHA Hazard

Irritant

HMIS Classification

Health: 2

Flammability: 0

Physical Hazard: 0

NFPA Rating

Health: 2

Fire:  0

Reactivity: 0

TSCA Status

Not On TSCA Inventory

Transportation Information

DOT (US)

IMDG

IATA

Not Dangerous Good

Not Dangerous Good

Not Dangerous Good

 

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