BZAR  [Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt]

Catalog ID: 6284 UNIT SIZE: 5 mg

BZAR  [Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt]

C48H52Cl2N10O9
983.89
N/A
N/A
1-4 ($133.00/Unit) 5-24 ($121.00/Unit) 25-49 ($84.00/Unit)

Description

BZAR is a fluorogenic enzyme substrate for serine proteases. BZAR is non-fluorescent and colorless until enzymatic activity results in cleavage of one of the amide bonds and converts the non-fluorescent bis-amide substrate into a highly fluorescent monoamide product. Enzymatic activity is detected by fluorescence with an excitation near 492 nm and emission near 523 nm. BZAR is recognized for providing much greater sensitivity to enzymatic activity than similar coumarin-based fluorogenic-enzymatic assays. BZAR is also a known inhibitor of guanidinobenzoatase activity in tumor cells. Please see other related products at the bottom of this page.

Documents

Safety Data Sheet
No Documents Available
Certificate of Analysis
No Documents Available
Product Manuals
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Images

No Images Available

Product Information

Product Size 5 mg
Form Solid
Absorption (estimated) Wavelength (λmax) 232 ± 3 nm
Fluorescence (estimated) Excitation / Emission maxima about 492 nm / 532 nm after enzymatic cleavage
Detection Method Fluorescent after enzymatic cleavage
Storage conditions Freeze: Store at -5 to -30°C (F)
Protect from moisture (D)
Protect from light (L)
Product Size Room temperature

 

Storage Condition

Protect from Light

 (PL)

Protect from Moisture

 (PM)

 Store at -20oC

  (F)

 

  • ((((3-Oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl)bis(azanediyl))bis(4-(((benzyloxy)carbonyl)amino)-5-oxopentane-5,1-diyl))bis(azanediyl))bis(aminomethaniminium) chloride

• Biochem J, 215, 253 (1983)
 
 
 
• Biochem J, 209, 299 (1983)

 

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For Research Use Only. Not for any animal or human therapeutic

or diagnostic use

No Animal source

Regulatory Compliance

6284

BZAR [Rhodamine 110, bis-(CBZ-L-argenine amide), dihydrochloride salt]

OSHA Hazard

No Known OSHA Hazards

HMIS Classification

Health: 0

Flammability: 0

Physical Hazard: 0

NFPA Rating

Health: 0

Fire:  0

Reactivity: 0

TSCA Status

Not On TSCA Inventory

Transportation Information

DOT (US)

IMDG

IATA

Not dangerous goods

Not dangerous goods

Not dangerous goods

 

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