DiOC2(3)

Catalog ID: 6322 UNIT SIZE: 1 g

DiOC2(3)

3,3'-Diethyloxacarbocyanine Iodide

C21H21IN2O2
460.31
905-96-4
MFCD00011952
1-4 ($100.00/Unit) 5-24 ($94.00/Unit)

Description

DiOC2(3) is a lipophilic, green-fluorescent dye that is commonly used as a membrane potential probe in bacteria and yeasts. Cationic DiOC2(3) accumulates in hyperpolarized cell membranes and aggregates in the lipid bilayer. The formation dye aggregates within the cell membrane leads to a decreased fluorescence intensity and red-shifted fluorescence emission. The red-shifting fluorescence emission has been utilized in ratiometric techniques to estimate cell membrane potentials that are precise and accurate. The fluorescence of these environment-sensitive dyes is greatly enhanced when incorporated into membranes or bound to lipophilic biomolecules such as proteins. They are weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. DiOC2(3) is excited near 482 nm and has an environmentally dependent fluorescence emission near 497 nm. Please see other related products below at the bottom of this page.

Documents

Safety Data Sheet
SDS: MSDS 6322.pdf
Certificate of Analysis
Lot Number: 50430
Product Manuals
No Documents Available

Images

No Images Available

Product Information

Product Size 1 g
Form Solid
Absorption (estimated) Wavelength (λmax) 482 ± 3 nm
Fluorescence (estimated) Wavelength (λmax) 497 ± 4 nm
Cell Permeability Cell membrane-permeant
Detection Method Fluorescent
Storage conditions Room temperature (RT)
Protect from moisture (D)
Protect from light (L)
Shipping conditions Room temperature

 

Storage Condition

Store Room Temp

(RT)

Protect from Moisture

(D)

Protect from Light

(L)

 

  • 3-Ethyl-2-[3-(3-ethyl-2(3H)-benzoxazolylidene)-1-propenyl]-benzoxazolium iodide      

     

• Tarasova NI, Seth R, Tarasov SG, Kosakowska-Cholody T, Hrycyna CA, Gottesman MM, Michejda CJ, J Med Chem, 48:3768-3775 (2005)
 
T.M.Kelly, D.F. O'Brien. Photog. Sci.Eng. 18,68 (1974)

 

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For Research Use Only. Not for any animal or human therapeutic or diagnostic use

No Animal source

Regulatory Compliance

6322

3,3'-Diethyloxacarbocyanine Iodide [DiOC2(3)]

OSHA Hazard

No Known hazards

HMIS Classification

Health: 2

Flammability: 0

Physical Hazard: 0

NFPA Rating

Health: 2

Fire:  0

Reactivity: 0

TSCA Status

Not On TSCA Inventory

 

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